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Psicothema was founded in Asturias (northern Spain) in 1989, and is published jointly by the Psychology Faculty of the University of Oviedo and the Psychological Association of the Principality of Asturias (Colegio Oficial de Psicología del Principado de Asturias).
We currently publish four issues per year, which accounts for some 100 articles annually. We admit work from both the basic and applied research fields, and from all areas of Psychology, all manuscripts being anonymously reviewed prior to publication.

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Semantic inhibition and dementia severity in Alzheimer’s disease

Teresa Cervera-Crespo1, Julio González-Álvarez1, and Vicente Rosell-Clarí2


1 Universitat de València and 2 Universitat Jaume I Castellón

Background: Semantic inhibition is often found to be impaired in Alzheimer’s disease (AD). The sentence completion task (Hayling test) was used to investigate whether it would be useful for differentiating mild AD from moderate AD. Method: Latency responses and error scores in the automatic and inhibition parts of the test were registered in these two groups of patients and in a group of healthy older participants. The types of errors were also analysed. Group differences were analysed by ANOVA. In addition, relationships with other neuropsychological tests were reported. Results: Participants with moderate AD performed worse than controls in both the automatic and inhibition sections, whereas participants with mild AD exhibited impaired performance in the inhibition part, but not in the automatic part. Differences between the groups with mild and moderate AD appeared only in the error scores in the inhibition part, specifically type 3 errors. Error scores in the inhibition part correlated with performance in verbal fluency and working memory tests. Conclusions: The Hayling task may be a useful tool for investigating control of inhibition in different stages of AD because different patterns of responses were observed.

Inhibición semántica y enfermedad de Alzheimer con diferentes grados de severidad. Antecedentes: los déficits en inhibición semántica en personas con enfermedad de Alzheimer (EA) son frecuentes. La tarea de completamiento de frases de Hayling se utilizó para determinar si ésta podría ser útil para diferenciar EA leve de EA moderado. Método: se compararon los tiempos de respuesta y el número de errores obtenidos en las partes automática e inhibición en los dos grupos de pacientes y en adultos mayores sanos. El tipo de errores fue también analizado. Las diferencias entre los grupos fueron analizadas mediante ANOVA. Además se obtuvieron las correlaciones con otros tests neuropsicológicos. Resultados: los pacientes con EA moderado mostraron peor ejecución en las dos partes: automática e inhibición, mientras que el grupo EA leve mostró déficits solo en inhibición. Los grupos leve y moderado se diferenciaron en el número de errores en inhibición, específicamente en errores tipo 3. El número de errores en inhibición correlacionó con fluencia verbal y memoria de trabajo. Conclusiones: la tarea Hayling podría ser útil para investigar control inhibitorio en diferentes etapas de la EA ya que se observaron diferentes patrones de respuesta.

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